Local officials quoted by the official Palestinian news agency Wafa said the vehicle overturned after Israeli forces directed it down what they described as an “unsafe road”.

Gaza Civil Defence spokesman Mahmud Bassal said that 20 people were killed and dozens were wounded in the incident while hundreds of civilians were waiting for aid, the AFP news agency reported.

“Despite the recent limited allowance of a few aid trucks, the occupation deliberately obstructs the safe passage and distribution of this aid,” the Gaza Government Media Office said in a statement.

“It forces drivers to navigate routes overcrowded with starving civilians who have been waiting for weeks for the most basic necessities. This often results in desperate crowds swarming the trucks and forcibly seizing their contents.”

The incident comes as humanitarian organisations warn of famine and disease spreading across the enclave, while deaths from starvation and malnutrition continue to rise.

At least three people died from malnutrition on Wednesday, medical sources told Al Jazeera. A source at al-Shifa Hospital in northern Gaza confirmed that Hiba Yasser Abu Naji, a child, died from malnutrition. An infant also died from malnutrition, according to the source. An adult from Jabalia was also reported to have died as a result of malnutrition.

Meanwhile, Palestinians approaching aid distribution sites run by the notorious GHF have frequently come under Israeli fire since the organisation launched operations in late May. Such shootings have become near-daily occurrences near its sites in central and southern Gaza.